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Zika Virus and Pregnancy: Risks, Prevention, and Care

By
Charles M. Carlsen
Published December 10, 2025
4 min read
Zika virus transmitted through mosquitoes, specifically the Aedes aegypti and Aedes albopictus. Zika comes with its own set of risks during pregnancy because it can affect an unborn child’s development in pregnancy. When the expectant mother has Zika, the virus can pass through the placenta they share and infect the fetus. This infection is associated with microcephaly – a condition in which a baby is born with a head that is not only smaller in size than other babies of the same age, but also points to a problem with the brain.
Microcephaly is actually just one part of what doctors now call congenital Zika syndrome and other problems might range from development delays, eye problems and even joint abnormalities. As recent cases have appeared and with ongoing worries over international travel, knowledge about Zika in pregnancy has emerged. It is particularly recommended that pregnant women should take precautions if they reside in these or are planning to travel to such countries. The fact that the health of a baby is at risk and these risks could lead to life-long complications. This has made prevention and early assessments necessary.

Why You Should Be Concerned About Zika During Pregnancy

Congenital abnormalities arising from Zika virus infection during fetal development can lead to numerous enhanced life defects that a fateful child may be born with. It has been established that Zika virus is devastating to the development of the fetus, principally due to the fact that it is most toxic to neural progenitor cells which are important for the development of the brain.
Why You Should Be Concerned About Zika During Pregnancy
Researchers have found that Zika exposure in the womb can also result in congenital Zika syndrome, encompassing multiple developmental and physical challenges. This syndrome may include severe brain malformations, decreased brain tissue, and visual or hearing impairments. More research has associated the virus with Guillain-Barré syndrome in infants, a situation that leads to muscle weakness and at times paralysis.
Key Statistics and Data
Pregnant women in Zika-prone areas are advised to take extra precautions to prevent infection, including avoiding travel to high-risk zones, using mosquito repellents, wearing long-sleeved clothing, and staying in air-conditioned or screened-in places.
For a mother affected with Zika virus the risk is not limited to the period of pregnancy. Affected kids commonly have some form of lifelong care, developmental intervention and schooling. It implies that families may be burdened with responsibilities throughout their lifetime, at great personal emotional and or financial loss. Such realities support the option of prenatal screening as well as early educational intervention in case of the exposure.

Ultrasound Scans and other Examinations During the First Twelve Months of life

For the purposes of early detection of all medical conditions that may develop from Zika infection, children who were born to mothers with Zika during pregnancy are subjected to a number of tests within their first year of life. The CDC suggests receiving at least six tests within the first month of life, which include physical assessments, head CT or ultrasound, eye exam, and hearing test. Every screening is supposed to identify some issue that may not be seen at first glance, and may be hazardous for the child’s further physical and mental development.
Explanation of Each Test
  • Head Ultrasound: Used to assess brain structure for signs of microcephaly or other malformations.
  • Eye Exam: Identifies retinal or optic nerve issues, as Zika can affect vision.
  • Hearing Test:  Facilitates identification of possible early signs of hearing loss which may impact on language acquisition.
  • Developmental Assessments: Used to screen the baby for developmental delay in language, motor and social domains and your pediatrician may order other tests to monitor the baby’s progress.
When the tests show that everything is not okay, children are referred to a neurologist or an eye doctor or any other developmental expert. Parents are encouraged to keep the child for follow-up because there might be new symptoms that emerge or check ups are done to assess the child’s growth.

Specialized Care and Coordination

Management of infants possibly affected by Zika virus during pregnancy requires extremely stringent approach and interprofessional collaboration. Zika infected children will likely have learning disabilities, neurological disorders and other congenital anomalies such as microcephaly and other developmental disabilities. Tailored attention may help to improve the developmental status of the infants and the overall life percentiles as infants are known to have numerous medical concerns that require attention from different technicians.
For infants suspected of congenital Zika syndrome, the first few days and weeks post-birth are critical for diagnosis. Comprehensive evaluations include precise head circumference measurements, hearing tests, and ophthalmologic exams, as some infants may show no immediate signs of complications. In contrast, others may have observable neurological abnormalities right away. Diagnostic imaging, such as head ultrasounds, is often used to detect brain abnormalities. Genetic consultations may also be recommended to rule out other possible causes of congenital abnormalities, like microcephaly, ensuring that any observed condition directly relates to Zika exposure rather than a different genetic or infectious cause​.

Role of Pediatric Specialists in Long-Term Monitoring

Infants affected by Zika benefit significantly from coordinated, specialized care that includes pediatric neurologists, infectious disease experts, developmental specialists, and occupational or physical therapists. For example, simple neurologic checks as well as developmental milestones are usually conducted at intervals of three to six monthly to assess motor and mental developments. Early intervention plans also have a significant role in assisting families manage their kid’s development through effective therapeutic procedures. In the same respect in case the child develops a disability or a delay in any of the developmental milestones the families are may require the services of the family services to provide a holistic and continuous support.

When to Seek Specialized Care and Monitoring

For children affected by Zika virus exposure during pregnancy, ongoing specialized care and monitoring can make a significant difference in developmental outcomes. Early and regular medical evaluations are crucial in tracking a child’s physical and neurological development, especially considering the potential complications associated with congenital Zika syndrome (CZS), such as microcephaly and other developmental disorders.

Importance of Early Monitoring

For children who were in utero exposed to Zika; continued outpatient specific developmental care and follow-up could greatly impact child development. There should be early and frequent health checkups for a child in order to evaluate their developmental progress concerning congenital Zika syndrome (CZS), including microcephaly or other neurological disorders. Since early intervention is key in shaping a child’s developmental path, many experts recommend frequent check-ups during the first few years of life. These evaluations, often monthly in the early stages, can later extend to quarterly visits as the child grows older, depending on individual needs.

Role of Ultrasound and Imaging

For children diagnosed with or at risk of microcephaly, ultrasound and MRI scans provide detailed insight into the brain's structure and growth patterns.
Ultrasound imaging is generally the first step, helping to determine head size and detect any abnormalities in brain development. MRI is especially useful in detecting cortical malformations or other subtle brain abnormalities that may not be visible in ultrasounds. Imaging assessments are typically recommended in the prenatal phase if the mother was exposed to Zika, with follow-up scans in infancy to track brain growth and detect any emerging abnormalities.

Guidance for Parents

Knowing when to consult specialists is essential for families navigating Zika-related challenges. Primary care physicians, pediatricians in particular, are solely responsible to educate parents on when to consult other doctors, for instance, neurologist for development of the brain, ophthalmologist for vision, and developmental pediatrician for motor and cognitive assessment. Parents too may find it useful to learn about these early indicators of developmental concerns as a way of addressing the problems in good time.
Checklist for Parents
Here are some signs that may indicate the need for specialized care:
  • Delayed Milestones: Delayed time to sit up, walk or even talk, might be indicators of developmental problems.
  • Muscle Tone Irregularities: Both low muscle tone or high may be suggestive of motor development difficulties.
  • Behavioral or Cognitive Delays: Delayed response to stimuli such as sound or sight, or difficulties in paying attention.
  • Frequent Seizures:  Any sort of seizure or tremor.

How to Protect Yourself and Your Baby from Zika Virus

Since Zika is transmitted by the Aedes mosquitoes which are predominantly active during the day, doing things that eliminate chances of mosquito bites is very important to safeguard the life of both mother and child.
  1. Avoiding Mosquito Bites: One of practical preventive measures includes the use of EPA registered mosquito repellent is an effective approach. Some repellents are safe in the course of pregnancy and they include DEET, picaridin and IR3535. Use long sleeves, clothing treated with permethrin, and mosquito nets, particularly if sleeping outdoors or in rooms with an open structure.
  2. Travel Precautions: Avoid going to areas that have increased cases of Zika infection especially during the first period of pregnancy. According to recent advisories, Zika is still active in places such as Central and South America, South East Asia, and Africa. Studying the CDC’s Zika travel alerts before scheduling a trip is something one should do because these alerts change depending on the data regarding symptom transmission.
  3. Prenatal Care’s Role:  Taking prenatal appointments frequently is very important when it comes to managing Zika risks because special care can be taken and other ultrasound and tests done if the woman has been exposed to Zika. Prenatal care should be taken regularly and scheduling an appointment frequently can help in early detection of any development issues that might be relating to pregnancy.

Follow-Up Care and Support for Families

Counseling and close follow-up after birth are very important for families who contracted the Zika virus as children may have developmental and emotional concerns as they age. Parents are advised to have their children with congenital Zika exposure be seen by the pediatricians later in their early childhood for developmental evaluations and or physical therapy among other tests that may be needed.
Ongoing Care Recommendations
Most pediatricians recommend their patients have a timetable or routine aftercare appointments especially in the early years. Children with Zika related impairments should have periodic neurological assessments by pediatric neurologists physical, and occupational therapy for emerging motor and cognitive difficulties. The goal directed interventions, specifically speech and motor skills support, are especially useful for enabling children to make developmental progress.
Psychosocial Support
Families coping with a Zika diagnosis face unique emotional and logistical challenges, which is why counseling can be incredibly helpful. Counseling which involves consulting with a professional in issues concerning child rearing and support groups so that the parents feel surrounded by people who understand their plight. The CDC and most local health departments are good first stops for families where they can find support groups, information about therapies, and service providers.

Key Support Resources

Medical Support Networks
  • Pediatric Specialty Centers: Major children's hospitals often have highly skilled Zika care teams with practitioners in different specialties.
  • Birth Defects Research Centers: These are centers which focus on monitoring development and may be able to implement unique therapeutic interventions
  • Telehealth Services: It’s now possible to book remote consultations with the Zika specialist available in many if the family resides in the rural area.
For immediate assistance:
  1. CDC Info Hotline: 1-800-CDC-INFO or 1-800-332-4636 (CDC’s 24-hour telephone information center)
  2. Local Health Department Directory: (Go to you state health department)
  3. Crisis Support: 211

Zika Virus Transmission Pathways

The most common way of getting infected with the Zika virus is through the blood sucking mosquitoes, specifically the aedes aegypti and the aedes albopictus species. These are day and night feeders and prefer tropical and subtropical climates, the same ones that transmit diseases like dengue and chikungunya. It is transmitted when a mosquito that is already infected with the virus feeds on an infected person thereby becoming infected with the virus and passes the virus to the next person it bites. This cycle enables the virus to persist within large mosquito populations, especially where there is lack of or little measures put in place to stop the spread of mosquitoes.
Apart from vector borne through mosquitoes there are other routes of transmission of Zika which include but are not limited to: vaginal, anal, and oral sex. This mode stresses protective practices, particularly when one of the partners has been in contact with the virus. Zika has also been found in saliva and urine although they are not regarded as principal mode of transmission. It has occasionally spread through blood transfusion, though due to regular tests, the spread of the virus is controlled.
Another critical pathway is vertical transmission, when an infected woman transfers the pathogen to her unborn child and gets congenital disorders such as microcephaly. These various modes of transmission show how lack of effective preventive measures that not only prevent contact with mosquitoes but also direct contact will help overcome this disease.

Global Travel Advisories and Current Zika-Endemic Regions

Zika virus outbreaks are at the moment being reported in different parts of the globe particularly in the tropical and subtropical areas that support breeding of Aedes mosquitoes. The CDC and who continuously publish travel information about areas with Zika virus transmission across South America, Central America, Southeast Asia, and the Caribbean. These advisories are helpful for pregnant women or those who intend to get pregnant, due to the dangers Zika poses to unborn babies.
Ideally, pregnant women are advised to refrain from visiting Zika-infected regions in order to hugely reduce chances of contraction of the virus. The CDC also commends a particular set of measures arriving from these areas can take to curb the spread through sexual contact since the virus remains in bodily fluids even after the symptoms have cleared.

Conclusion

Given the result of the global surveillance data, Zika virus transmission has yet to reduce since its peak during 2015-2016, with more than 87 countries and territories still experiencing Zika virus circulation, especially in Southeast Asia and South America. From getting a sample and preparing a rapid diagnostic test kit, laboratories now take between 4 hours to get results, compared to 7-10 days as was common a few years ago.
The risks of Zika are still present and that identifying patients early in the course of their disease is vital. Vaccine remains under development, but multiple candidates for the vaccine are in the Phase II trials, so the emphasis is on prevention and multidisciplinary approach.

REFERENCES

1.“Congenital Zika Syndrome and Other Birth Defects.” Zika Virus, 31 May 2024,
2.“Find the Repellent That Is Right for You | US EPA.” US EPA, 10 Sept. 2024,
3. Jones, H. Royden. “Guillain-Barré Syndrome: Perspectives With Infants and Children.” Seminars in Pediatric Neurology, vol. 7, no. 2, June 2000, pp. 91–102.
4. Microcephaly.” Birth Defects, 16 May 2024,
5. Microcephaly - Symptoms and Causes - Mayo Clinic.” Mayo Clinic, 26 May 2022,
6.  Zika Travel Information | Travelers’ Health | CDC.” CDC.gov,
Charles M. Carlsen
Co-Founder of Dr.Sono
Hello! I'm Charles, As co-founder of Drsono, I contribute to the DRSONO blog, providing valuable insights and up-to-date information on ultrasound technology and diagnostic imaging.

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